Message to the FDA on ESAs: REMS Is Not Enough, More Studies Are Needed

Message to the FDA on ESAs: REMS is not enough, more studies are needed.

S ince March 24, 2010, the Food and Drug Administration (FDA) has been requiring a “Risk Evaluation and Mitigation Strategy” (REMS) for all patients who are treated with erythropoiesis-stimulating agents (ESAs) (1). Although regulatory authorities elsewhere in the world have not as yet taken this approach, experience suggests that these agencies often take their cues from the FDA. Most nephrolo...

How Much Is Enough… What More Is Needed?

Editorial: New Iranian Strategic Plan on Addiction Biology Studies Has a Clear Message for Neuroscientists “Your Help is Seriously Needed”

The fifth Iranian national congress on the biology of addiction was held in 22-24 June 2011 in Tehran University of Medical Sciences with over 100 valuable oral and poster presentations and over 300 participants. One of the main sessions of the congress was devoted to a national strategic planning and Iranian Drug Control Head Quarter (DCHQ) introducing the first national executive road map on ...

Energy Efficiency Is Not Enough, Energy Proportionality Is Needed!

Due to the energy consumption/resource utilization characteristics of todays centralized DB servers, the fastest configuration is also the most energy-efficient one. Extensive use of SSDs alone cannot enable a fundamental change of this overall picture, because the storagerelated energy consumption is typically only a little fraction of the overall energy budget. Even, when this storage-related...

More palliative care specialists is not enough.